10 strangers are summoned to a remote island and while they are waiting for the mysterious host to appear, a recording levels serious accusations at each of the guests, including Judge Francis J. Quinncannon and Dr. Edward G. Armstrong, and soon they start being murdered, one by one. As the survivors try to keep their wits, they reach a disturbing conclusion: one of them must be the killer.

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Ten strangers, drawn away from their normal lives to an isolated rock off the Devon coast. But as the mismatched group waits for the arrival of the hosts — the improbably named Mr. and Mrs. U.N. Owen — the weather sours and they find themselves cut off from civilization. Very soon, the guests, each struggling with their conscience, will start to die — one by one, according to the rules of the nursery rhyme ‘Ten Little Soldier Boys’ — a rhyme that hangs in every room of the house and ends with the most terrifying words of all: ‘… and then there were none.